Baszucki Biobank
at Stanford Vascular
The mission of the Baszucki Biobank is to advance biomedical
vascular research by integrating excellence and innovation, accelerating therapeutic breakthroughs in translational research and personalized medicine for vascular patients.
Overview
The Stanford Vascular Biobank is a repository of vascular samples including blood and tissue aimed at advancing research on peripheral artery disease, carotid artery disease, and aneurysms. By studying these samples, researchers can uncover the causes of vascular diseases, develop new drugs and therapies, and gain insights into the genetic factors that influence vascular health. This knowledge helps create personalized treatment approaches for patients. Since 2022, we have consented and collected samples from over 400 vascular patients.
History & The Baszucki Family
The Baszucki Family Surgery biobank was established in the fall of 2021 with the generous support of Mr. Paul Baszucki.
“The extended Baszucki Family supports a number of philanthropic health care initiatives. As a patient of Doctor Lee I witnessed a high level of dedication, skill and care combined with leading edge stent technology for an excellent outcome. I was very appreciative and wanted to support Doctor Lee in his quest for advancement of vascular health and care.” - Paul Baszucki.
How Samples are Used in Research
Genomics and Patient-specific induced pluripotent stem cells (iPSC) are being generated to understand vascular disease mechanisms and develop better therapeutic and medical care.
Breakthroughs & Notable Outcomes
Cardiovascular Research Volume 3 Issue 10, October 2024. The research study explores the mechanisms of cardiac injury in long COVID, with a focus on the role of endothelial cells (ECs). Dr. Sayed and his team uncovered how cytokines released by ECs, particularly CCL2, contribute to cardiac dysfunction. Their research, utilizing advanced models like thrombotic vascular tissues and cardiac organoids, highlights the critical role of CCL2-induced oxidative stress in promoting cardiac injury. This work underscores the importance of early vascular health monitoring in long COVID patients.
Our Team
Leadership
Jason Lee, MD
Professor of Surgery
Director of Endovascular Surgery
Chief Division of Vascular Surgery
Nazish Sayed, MD
Assistant Professor of Surgery
Director Vascular Biobank