Zhou Research Lab
Description
Dr. Zhou’s vascular research laboratory focuses on pathogenesis of atherosclerotic lesion formation and molecular mechanisms of intimal hyperplasia, including smooth muscle cell proliferation, oxidative stress, and endothelial cell dysfunction. Our specific clinical research interests are re-stenosis following endovascular interventions and plaque progression in arterial trees. Through collaboration with Stanford investigators and investigators at Baylor College of Medicine, plaque morphology and radiographic imaging are correlated. Furthermore, innovational treatment approaches for cardiovascular diseases are investigated using a well-developed wire-injury rodent model.
Personnel
- Wei Zhou, MD: Principal Investigator
- Hong Chai, MD, PhD: Senior Research Scientist
- Joel Morrisett, MD: Consultant, Baylor College of Medicine
Research Funding
- 2007-2009:
Principal Investigator, Soluble CD40L induces restenosis after vascular injury. Palo Alto Institute for Research & Education. - 2007-2009:
Principal Investigator, Embolic Protection Device Prevents Distal Embolization for High-Risk Lesions during Lower Extremity Percutaneous Interventions. American College of Surgeon Faculty Research Fellowship.
Clinical Trials
- OVER
- PROOF
- PROTECT
- CORAL
- GENZYME
- ANGIOTECH
For information about enrolling in these Clinical Trials at the VAPAHCS, please contact:
Dona Bahmani, Clinical Research Coordinator at VAPAHCS
(650) 849-0357
